Short Communication Age-dependent Alterations in Human Per2 Levels after Early Morning Blue Light Exposure
نویسندگان
چکیده
Corinne Jud, Sylvie Chappuis, Victoria L. Revell, Tracey L. Sletten, Dirk-Jan Saaltink, Christian Cajochen, Debra J. Skene, and Urs Albrecht Department of Medicine, Unit of Biochemistry, University of Fribourg, Fribourg, Switzerland Centre for Chronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom Centre for Chronobiology, Psychiatric Hospital of the University of Basel, Switzerland
منابع مشابه
Age-dependent alterations in human PER2 levels after early morning blue light exposure.
In our modern society, we are exposed to different artificial light sources that could potentially lead to disturbances of circadian rhythms and, hence, represent a risk for health and welfare. Investigating the acute impact of light on clock-gene expression may thus help us to better understand the mechanisms underlying disorders rooted in the circadian system. Here, we show an overall signifi...
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متن کاملEvening exposure to blue light stimulates the expression of the clock gene PER2 in humans.
We developed a non-invasive method to measure and quantify human circadian PER2 gene expression in oral mucosa samples and show that this gene oscillates in a circadian (= about a day) fashion. We also have the first evidence that induction of human PER2 expression is stimulated by exposing subjects to 2 h of light in the evening. This increase in PER2 expression was statistically significant i...
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تاریخ انتشار 2009